Manabu Kawada Selected Research

Androgens

1/2023	Deoxynortryptoquivaline: A unique antiprostate cancer agent.
10/2021	Androprostamine A: a unique antiprostate cancer agent.
4/2015	Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp. MK932-CF8.
7/2008	A new terrein glucoside, a novel inhibitor of angiogenin secretion in tumor angiogenesis.
3/2007	Highly tumorigenic human androgen receptor-positive prostate cancer cells overexpress angiogenin.
10/2006	Establishment of a highly tumorigenic LNCaP cell line having inflammatory cytokine resistance.
2/2004	Ectopic expression of the amino-terminal peptide of androgen receptor leads to androgen receptor dysfunction and inhibition of androgen receptor-mediated prostate cancer growth.
7/2003	Androgen-independent prostate cancer DU145 cells suppress androgen-dependent growth of prostate stromal cells through production of inhibitory factors for androgen responsiveness.

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Manabu Kawada Research Topics

Disease

80	Neoplasms (Cancer) 11/2023 - 03/2002
19	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 07/2003
13	Neoplasm Metastasis (Metastasis) 02/2022 - 02/2003
12	Pancreatic Neoplasms (Pancreatic Cancer) 11/2023 - 04/2006
9	Stomach Neoplasms (Stomach Cancer) 09/2023 - 01/2015
8	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 09/2013
8	Squamous Cell Carcinoma of Head and Neck 02/2022 - 04/2018
7	Colonic Neoplasms (Colon Cancer) 08/2021 - 10/2002
5	Carcinoma (Carcinomatosis) 11/2022 - 05/2004
5	Breast Neoplasms (Breast Cancer) 11/2022 - 06/2020
5	Mouth Neoplasms (Oral Cancer) 12/2020 - 09/2018
4	Lung Neoplasms (Lung Cancer) 02/2023 - 04/2006
4	Carcinogenesis 01/2023 - 04/2017
4	Infections 01/2023 - 07/2017
4	Glioblastoma (Glioblastoma Multiforme) 10/2021 - 01/2016
4	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 07/2020 - 04/2015
3	Melanoma (Melanoma, Malignant) 12/2020 - 03/2019
2	Hepatocellular Carcinoma (Hepatoma) 11/2023 - 04/2017
2	Renal Cell Carcinoma (Grawitz Tumor) 12/2022 - 04/2022
2	Osteosarcoma (Osteogenic Sarcoma) 02/2022 - 12/2021
2	Adenocarcinoma 08/2021 - 12/2020
2	Parasitic Diseases (Parasitic Disease) 01/2021 - 01/2019
2	Rheumatoid Arthritis 01/2021 - 01/2019
2	Brain Neoplasms (Brain Tumor) 10/2020 - 08/2017
2	Atopic Dermatitis (Atopic Eczema) 10/2010 - 02/2009
1	Sickle Cell Anemia (Hemoglobin S Disease) 12/2023
1	Wound Infection (Wound Infections) 01/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Wounds and Injuries (Trauma) 01/2023
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 04/2022
1	Triple Negative Breast Neoplasms 02/2022

Drug/Important Bio-Agent (IBA)

30	Monoclonal AntibodiesIBA 09/2023 - 11/2017
21	Immunoglobulin G (IgG)IBA 02/2023 - 04/2019
14	Proteins (Proteins, Gene)FDA Link 06/2023 - 03/2002
9	human ERBB2 proteinIBA 09/2023 - 08/2019
9	Complement System Proteins (Complement)IBA 11/2022 - 11/2017
8	Trastuzumab (Herceptin)FDA Link 09/2023 - 08/2019
8	AndrogensIBA 01/2023 - 07/2003
7	ErbB Receptors (EGF Receptor)IBA 06/2022 - 08/2020
5	Glycoproteins (Glycoprotein)IBA 02/2023 - 09/2018
5	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 02/2004
5	intervenolinIBA 12/2021 - 05/2013
5	Insulin-Like Growth Factor I (IGF-1)IBA 01/2020 - 04/2006
4	Antineoplastic Agents (Antineoplastics)IBA 11/2023 - 02/2005
4	Epithelial Cell Adhesion MoleculeIBA 01/2023 - 12/2020
4	podocalyxinIBA 12/2020 - 08/2017
3	Phosphotransferases (Kinase)IBA 06/2023 - 08/2002
3	CeramidasesIBA 01/2023 - 02/2009
3	Peptides (Polypeptides)IBA 10/2022 - 02/2004
3	cytostatinIBA 10/2021 - 02/2003
3	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 10/2021 - 02/2003
3	Auranofin (Ridaura)FDA Link 01/2021 - 01/2019
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 12/2020
2	Conditioned Culture MediaIBA 11/2023 - 11/2018
2	epidermal growth factor receptor VIIIIBA 11/2023 - 01/2016
2	ertredinIBA 11/2023 - 01/2016
2	Immunoconjugates (Immunoconjugate)IBA 02/2023 - 04/2020
2	Dihydroorotate DehydrogenaseIBA 01/2023 - 11/2021
2	pyrimidineIBA 01/2023 - 11/2021
2	AntigensIBA 11/2022 - 10/2020
2	AntibodiesIBA 04/2022 - 08/2020
2	androprostamine AIBA 10/2021 - 10/2021
2	Protein Isoforms (Isoforms)IBA 11/2020 - 01/2020
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 09/2017
2	Insulin-Like PeptidesIBA 01/2020 - 04/2006
2	leucinostatin AIBA 01/2020 - 02/2010
2	adenovirus receptorIBA 11/2019 - 11/2017
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 07/2017 - 04/2015
2	Proteasome InhibitorsIBA 08/2016 - 04/2007
2	CyclinsIBA 08/2016 - 03/2002
2	Interleukin-6 (Interleukin 6)IBA 01/2015 - 10/2006
2	phthoxazolinIBA 01/2009 - 05/2004
2	angiogeninIBA 07/2008 - 03/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2007 - 03/2002
2	CytokinesIBA 10/2006 - 02/2003
1	GlobinsIBA 12/2023
1	oligomycin sensitivity-conferring protein (complex V)IBA 11/2023
1	oligomycin AIBA 11/2023
1	A-factor (Streptomyces)IBA 11/2023
1	pertuzumabIBA 09/2023
1	Tyrosine Kinase InhibitorsIBA 06/2023
1	Tyrosine (L-Tyrosine)FDA Link 06/2023
1	Oncostatin MIBA 06/2023
1	Insulin Receptor Substrate ProteinsIBA 06/2023
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2023
1	vandetanib (ZD6474)IBA 06/2023
1	Indicators and Reagents (Reagents)IBA 01/2023
1	LipidsIBA 01/2023
1	EnzymesIBA 01/2023
1	2,6-dinitrotoluene (DNT)IBA 01/2023
1	Epidermal Growth Factor (EGF)IBA 11/2022
1	Amino Acids FDA Link 10/2022
1	Surface Antigens (Surface Antigen)IBA 02/2022
1	elaiophylinIBA 01/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2021

Therapy/Procedure

21	Therapeutics 01/2023 - 11/2006
3	Transplantation 07/2020 - 04/2015
2	Oral Administration 01/2021 - 04/2006
1	Surgical Amputation (Amputations) 01/2023